NeoFitoroid BioOintment
Haemorrhoidal discomfort. Soothes pain, burning and itching while protecting the mucosa.
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NeoFitoroid BioOintment is made with plant-based molecular complexes that soothe and protect the anorectal mucosa and is used to counteract the ailments (pain, stinging and itching), irritation and inflammation that accompany haemorrhoids.
INSTRUCTIONS:
NeoFitoroid BioOintment is indicated for the treatment of (internal and external) haemorrhoids and for the accompanying symptoms such as pain, stinging, and anal and perianal itching. Can be used even when anal fissures are present.
NeoFitoroid BioOintment can also be used in prevention and in all cases that may result in irritation and/or congestion of the anal and perianal area (constipation, diarrhoea, and an incorrect diet and lifestyle). NeoFitoroid BioOintment is also suitable for use during pregnancy and breastfeeding.
HOW IT WORKS:
The beneficial effect of NeoFitoroid is provided by Helydol®, a lyophilized extract consisting of the purified lipophilic fraction of a specific selection of Helichrysum that, enriched with Aloe, Ruscus, vegetable oils and essential oils, soothes the irritation, protecting the mucosa and helping it to return to normal through 3 mechanisms of action:
- Mucoadhesive: adheres to the mucosa, forming a protective film and protecting it against contact with irritants;
- Lubricant: reduces the friction created by faeces, thereby guarding against irritation and perianal congestion;
- Antioxidant: protects the mucosa from free radicals.
In addition, NeoFitoroid creates an environment that is unfavourable for the growth of microorganisms, producing a further protective effect and reducing itching. Its refreshing properties offer rapid relief from the discomfort.
NeoFitoroid does not contain corticosteroids or anaesthetics and, thanks to its mechanism of action, does not dry out the mucosa.
Read the warnings and instructions for use carefully.
Instructions for use
For external application, apply and massage gently over the anal and perianal region. For internal application, screw the rectal cannula onto the tube. Apply a sufficient quantity of the ointment to cover the affected area. Use the product after emptying the bowel and washing the anal and perianal area carefully and gently. To prevent irritation caused by friction, the treatment can be applied before emptying the bowel. In any event, the product should be applied after evacuation as well.
After use, unscrew the cannula, clean it thoroughly with warm water and soap and close the tube of ointment. Application may be repeated multiple times a day, including at short intervals, and for prolonger periods of time.
Ingredients
Functional ingredients: lyophilized extract of Helichrysum tips lipophilic fraction (Helydol®)* and Ruscus root*; Dehydrated leaf gel from Aloe vera*; Aqueous solution of Helichrysum tips*; Oily extract of hypericum tips*; Jojoba oil*; Karitè butter*; Essential oils: Melaleuca, Cypress and Peppermint.
Also contains: glyceryl stearate, caprylic/capric triglyceride, sucrose distearate, sucrose stearate, cetyl stearyl alcohol, vegetable glycerine, trihydroxystearin, vegetable oils, hydrogenated vegetable oils, candelilla wax, xanthan gum, citric acid, tocopherols, sodium silicate, benzyl acohol, potassium sorbate, sodium dehydroacetate, Sunflower oil.
*Ingredient from Organic Farming
Does not contain SLS and SLES, petroleum derivatives, parabens, PEG, colourants and synthetic perfumes.
Warnings
Do not use in case of individual hypersensitivity or allergy to one or more components. In the event that symptoms don't improve, seek medical advice.
Store at room temperature, away from heat sources and protected from light. Keep out of reach of children. The expiration date applies when the product is intact and stored properly.
Scientific evidence
EFFICACY TEST
- EVIDENCE OF EFFICACY IN ORDINARY EVERYDAY USE
The efficacy of NeoFitoroid endorectal ointment is supported by 71 clinical cases collected from patients with haemorrhoids and rhagades, thanks to the cooperation of general practitioners, a gastroenterologist a gynaecologist and a proctologist The product was recommended for 10 days at the dosage indicated on the label of 4 applications per day. The results described were achieved after 3 days of treatment on average.
RESULTS
NeoFitoroid improves the general well-being of patients with haemorrhoids and rhagades. Before treatment 79% of the patients described their condition as terrible/insufficient. After 3 days of treatment with NeoFitoroid 80.3% of patients with haemorrhoids described their overall well-being as GOOD to EXCELLENT.
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In 88% of patients it alleviates symptoms connected to evacuation, such as pain and bleeding, bringing the average disorder from moderate (3.2) to mild (1). The number of patients with symptoms absent went from 8 to 34.
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In 71% of patients it alleviates the discomfort perceived over the course of the day (itching, stinging, pain and sense of irritation) reducing the discomfort from moderate (6.2) to mild (2).
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- TOLERABILITY TEST EXECUTED IN ABOCA CELLULAR BIOLOGY LABORATORIES (NATURAL BIO MEDICINE)
NeoFitoroid ointment, after a 24-hour incubation with intestinal mucosal cells (intestinal epithelial cells and fibroblasts), is well tolerated and does not interfere with the vitality of mucosal cells.
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Optical fluorescence microscopy images show that after treatment with NeoFitoroid, the number and morphology of both fibroblasts and intestinal cells is nearly identical to untreated cells.
On the other hand, the images pertaining to other anti-haemorrhoidal products show a significant reduction in the number of cells present, in one or both tests, which indicates lower tolerability.
- NEOFITOROID ENDORECTAL BIO-OINTMENT COUNTERACTS THE ADHESION TO THE INTESTINAL MUCOSA OF THE MAIN MICROORGANISMS RESPONSIBLE FOR ITCHING.
An innovative in vitro anti-adhesion test shows that NeoFitoroid reduces adhesion to Caco-2 intestinal mucosal cells by 77% for Escherichia coli and by 88% for Candida albicans. The treatment calls for one hour of contact at 37 °C between the cells with the microorganisms and NeoFitoroid. After washing, fixation and staining the cells are observed under an optical microscope and the adhesion index – the number of microbial cells that adhere to every 100 Caco-2 intestinal cells – is evaluated.
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- NEOFITOROID ENDORECTAL BIO-OINTMENT ADHERES TO THE MUCOSA AND FORMS A FILM WITH A BARRIER EFFECT
NeoFitoroid, in the 1:2 dilution that simulates the ointment in vivo, adheres to 74.5% of the sites available on the mucosa.
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Furthermore, it continues to adhere for over 2 hours, even when subjected to a continues flow of a 2% mucin solution that simulates rectal fluid.
Finally, the barrier effect has been demonstrated: NeoFitoroid protects the mucosa against attack by inflammatory agents. In fact, in vitro testing shows an 80% reduction in the production of interleukin 6 induced by inflammatory agent LPS.
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- NEOFITOROID ENDORECTAL BIO-OINTMENT COUNTERACTS THE FREE RADICALS THAT FUEL THE INFLAMMATORY PROCESS
Antioxidant activity tests show that at 60 minutes after application, NeoFitoroid BioOintment still has a radical scavenger effect that is 60% that of vitamin C.